Bio Contaminants

Here is the list of biologically active substances fungal or bacterial origin that identified as the main substances of concern

Lipopolysaccharides

Endotoxin

Bacterial Pyrogen

872-05-9

…………………………………………………..

Molecular Weight: 5227 g/mol

Instruments/Method: Amebocyte Lysate Assays

Inhalation Acute Reference Concentration (RfCa) (mg/m^3)

ND

Inhalation Chronic Reference Concentration (RfC) (mg/m^3)

ND

Endotoxin

Bacterial Pyrogen

872-05-9

…………………………………………………..

Molecular Weight: 5227 g/mol

Instruments/Method: Amebocyte Lysate Assays

Inhalation Acute Reference Concentration (RfCa) (mg/m^3)

ND

Inhalation Chronic Reference Concentration (RfC) (mg/m^3)

ND

Biogenic Volatile Organic Compaunds (BVOC)

Phenylacetaldehyde

Hyacinthin

122-78-1

Molecular Weight: 120.15 g/mol

Boiling Point: 195 °C

Instruments: GC-MS

Inhalation Acute Reference Concentration (RfCa) (mg/m^3)

ND

Inhalation Chronic Reference Concentration (RfC) (mg/m^3)

ND

Metabolite

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Mycotoxins

Aflatoxins B1

AFB1

1162-65-8

…………………………………………………..

Molecular Weight: 312.27 g/mol

Instruments: Thin-layer Chromatography with Laser Induced Fluorescence Spectrometric Detection; HPLC

Inhalation Acute Reference Concentration (RfCa) (mg/m^3)

Neurotoxin

Inhalation Chronic Reference Concentration (RfC) (mg/m^3)

ND

Aspergillus flavus

A. parasiticus

.....................................................

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Aflatoxin G1

Aflatoxin, crude

1402-68-2

…………………………………………………..

Molecular Weight: 328.27 g/mol

Instruments: Thin-layer Chromatography with Laser Induced Fluorescence Spectrometric Detection; HPLC

Inhalation Acute Reference Concentration (RfCa) (mg/m^3)

Neurotoxin

Inhalation Chronic Reference Concentration (RfC) (mg/m^3)

ND

A. flavus,

A. parasiticus,

A. nomius,

A. pseudotamarii,

A. bombycis,

A. ochraceoroseus,

A. australis.

A. flavus

A. parasiticus

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Ochratoxin A

Phenylalanine

303-47-9

…………………………………………………..

Molecular Weight: 403.8 g/mol

Instruments: GC-MS

Inhalation Acute Reference Concentration (RfCa) (mg/m^3)

ND

Inhalation Chronic Reference Concentration (RfC) (mg/m^3)

ND

Aspergillus ochraceus Wilh,

A. sulphureus,

A. melleus,

Penicillium viridicatum Westling,

P. verrucosum

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NSD - nitrogen selective detector